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https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1494965618950-U5UEHWNGHQYR21EDILNQ/lab-mouse.jpg Wound Healing https://www.bridgepts.com/pig-scarring-and-reduction daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492548395711-RN5TLF42LMWPY27K2SVQ/pig-scarring1.jpg Pig Scarring and Scarring Reduction https://www.bridgepts.com/pig-acute-wound-healing daily 0.75 2020-01-30 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1567795903883-F4YEUC0YTKA5PONLEKQA/Acute+wound+figure2.jpg Pig Acute Wound Healing Figure 2. A retrospective analysis of 295 untreated, control wounds from 9 studies over 6 years. The data very closely approximates a typical healing curve with the slow “Inflammatory” phase followed by the rapid “Regenerative” phase and the “Remodeling” tail-end clearly discernible. Three linear regression lines have been included – one representing the period from Day 0 to Day 4 (Blue), demonstrating the Inflammatory phase, one representing the period from Day 4 to Day 14 (Orange), demonstrating the Re-epithelialization phase, and the third representing the period from Day 14 to Day 24 (Green), demonstrating the Remodeling phase of healing. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1567795866800-4O3H8J408EH7EJJWGYB7/Acute+wound+figure+1.jpg Pig Acute Wound Healing Figure 1. A comparison of total wound area as a percentage of Day 0 wound area. Two test materials were compared to a predicate material. https://www.bridgepts.com/rodent-lung-infection-animal-model daily 0.75 2017-04-18 https://www.bridgepts.com/rodent-implantable-biofilm-coated-devices daily 0.75 2020-08-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1597938901934-EWVG6E404585C4VUM3F1/Implant+Rodent+Biofilm+2.jpg Rodent Implantable Biofilm Coated Devices Figure 2. A comparison of total Staphylococcus colony forming units (CFUs) present on a silicone mesh inoculated with varying concentrations of S. aureus. Meshes were sampled at Day 7 and compared to control meshes that were not implanted and were sampled on Day 0. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1597938884295-8KXXHIUCJIOTQVXLP5Q9/Implant+Rodent+Biofilm+1.jpg Rodent Implantable Biofilm Coated Devices Figure 1. A comparison of total bioburden present on a silicone mesh inoculated with varying concentrations of S. aureus. Meshes were sampled at Day 7 and compared to control meshes that were not implanted and were sampled on Day 0. https://www.bridgepts.com/infection-control-biofilms daily 0.75 2025-10-21 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492550733500-WDS5UXYCFL2G0WTRSHS8/img-02-blue.jpg Infection Control & Biofilms https://www.bridgepts.com/rodent-transcutaneous daily 0.75 2017-04-18 https://www.bridgepts.com/customized-surgical-work daily 0.75 2020-08-19 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492552518630-ODTYRQKXXQXB8M9A1F7X/img-03-curgical.jpg Customized Surgical Work https://www.bridgepts.com/our-facility daily 0.75 2025-08-19 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1755628564547-EKA7CWT6NKXP11UV3659/OR1+%285%29.JPG Our Facility https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1755628564561-V8WT1V90KFX8DITBEHEI/OR1+%284%29.JPG Our Facility https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1755628571552-DB84DMJ8FV5NEJB1LZBF/Necropsy+%282%29.JPG Our Facility https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1755628571872-6QK2ZT1OV3SNJ1BS196N/Lab+%284%29.JPG Our Facility https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1755628580229-5SA8W3RKG20U78D853SY/Animal+Room+129+%284%29.JPG Our Facility https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1755628580180-8URSVT80B219MXVING31/Animal+Room+126+%287%29.JPG Our Facility https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1755628584906-XV6MR4XD3FY9C04YROXQ/Animal+Room+126+%283%29.JPG Our Facility https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492554660096-12N3UK0KYR8SUMPWE8XI/iStock-665692678.jpg Our Facility https://www.bridgepts.com/pig-infected-wound-healing daily 0.75 2020-04-16 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492706393885-DLDFS4GY5IO057M90FTA/image-asset.jpeg Pig Infected Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492706362810-P1PU0KX7UT29D8MSJ0HW/image-asset.jpeg Pig Infected Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492706318124-AFVN8BRTU4C3I29ZVPSE/image-asset.jpeg Pig Infected Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492706421450-R4DOMN59TSZI12T7OUH9/image-asset.jpeg Pig Infected Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492706464473-Q5C4DZZWA3T77QWJUFSS/image-asset.jpeg Pig Infected Wound Healing Biofilm in an infected, non-treated wound 5 days after inoculation with Staph and Pseudomonas https://www.bridgepts.com/pig-delayed-wound-healing daily 0.75 2018-04-05 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1522939238632-F2J3HABN9OBI8RDPUY45/Delayed+healing+by+varying+percentage.jpg Pig Delayed Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1522940395568-G2TRTFPGQ43I3SQTOUI3/Recovered+Total+Bacteria+in+Crosslinked+Wounds.jpg Pig Delayed Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1522945451430-IXS2HZX9QSGNLKOQBENY/Recovered+e.+coli+in+crosslinked+wounds.jpg Pig Delayed Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1522945451534-1LQ3N43K9V3P2XTFC6BM/recovered+p.+aeru+in+crosslinked+wounds.jpg Pig Delayed Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1522945452063-KGOWUFAC65YVBAU0GPTD/recovered+staph+in+crosslinked+wounds.jpg Pig Delayed Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1522939208733-N17EXP8B75JT6RGIJ2L0/Wound+healing+with+debridement.png Pig Delayed Wound Healing https://www.bridgepts.com/pig-debridement-effectiveness daily 0.75 2020-04-16 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1587048365019-EWDRBJ47Y41ZMXRUUXWE/Debridment+1.jpg Pig Debridement Effectiveness Figure 1. A comparison of median visual assessments of eschar formation of acute thermal injuries. Three concentrations of the same material were compared to a non-treated control. https://www.bridgepts.com/porcine-acute-thermal-injury-healing daily 0.75 2020-04-16 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1587049159605-CMV22P4LP7WFWPD1P21P/Burn+healing+1.jpg Pig Acute Thermal Injury Healing Figure 1. A comparison of average wound size compared to day 0 of acute thermal injuries. Three concentrations of the same material were compared to a non-treated control. https://www.bridgepts.com/pig-infected-thermal-injury-healing daily 0.75 2020-04-16 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1587047254727-1KDJIH399O46K9YQAE3U/Burn+Infect+1.jpg Pig Infected Thermal Injury Healing Figure 1. A comparison of total bioburden of wounds treated 24 hours post-infection (t=0) of acute thermal injuries. Biopsies were taken at three timepoints to assess the bioburden of the wounds. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1587047273419-FP1UCP5S6TGB9AXW55U6/Burn+Infect+2.jpg Pig Infected Thermal Injury Healing Figure 2. A comparison of Staphylococcus bioburden of wounds treated 24 hours post-infection (t=0) of acute thermal injuries. Biopsies were taken at three timepoints to assess the bioburden of the wounds. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1587047290634-F2QIBJCYXWR2E45D1ZJ3/Infect+burn+3.jpg Pig Infected Thermal Injury Healing Figure 3. A comparison of Pseudomonas bioburden of wounds treated 24 hours post-infection (t=0) of acute thermal injuries. Biopsies were taken at three timepoints to assess the bioburden of the wounds. https://www.bridgepts.com/goat-infected-bone-healing daily 0.75 2017-04-20 https://www.bridgepts.com/rat-infected-bone-healing daily 0.75 2017-04-20 https://www.bridgepts.com/tensile-testing daily 0.75 2017-04-20 https://www.bridgepts.com/rabbit-femur-defect daily 0.75 2017-04-20 https://www.bridgepts.com/walker-mason-burn-and-infection-model daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492710557995-58OOGRZGAWKWMCYPR1QS/image-asset.png Walker-Mason Burn and Infection Model https://www.bridgepts.com/rabbit-sidewall-adhesion daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492711532975-9EWI7XCL2HPJDE2DLHJ1/image-asset.jpeg Rabbit Sidewall (cecal) Adhesion Coated implant- no adhesion https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492711554423-WF4AC8M21AJ9P6ODXU0H/image-asset.jpeg Rabbit Sidewall (cecal) Adhesion Non-coated (control) implant- adhesions present https://www.bridgepts.com/rabbit-bone-allograft daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492715911693-MP65CJY5T6HE2PYFQCMV/image-asset.jpeg Rabbit Bone Allograft NOTE: Yellow highlights indicate that a given test article has achieved a statistical significance of p < 0.05 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492715896917-IML3T9KT6IEY7UXLKQL3/image-asset.jpeg Rabbit Bone Allograft https://www.bridgepts.com/rat-ischemic-wound-healing daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492717649738-3TVS0LBHRS30SBLQE5Q7/ischemic-fig-2.jpg Rat Ischemic Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492717456169-SITX5OWT91KJHXAFTJCB/image-asset.jpeg Rat Ischemic Wound Healing https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492717536665-64HP8KQIS8ILUZYKPWTB/image-asset.jpeg Rat Ischemic Wound Healing https://www.bridgepts.com/rat-franz-rovson-laparotomy-model daily 0.75 2018-03-09 https://www.bridgepts.com/pig-anastomosis-model daily 0.75 2019-09-05 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1567691801160-LAK9FP5QYN02DY8S4ZEB/Anastomosis+data+for+website+-+1.jpg Pig Anastomosis Model Figure 1. A burst test measuring the Median PSI at the time of failure. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1567691877804-9S9REN4AYXR44WDFXT9O/Anastomosis+data+for+website+-+2.jpg Pig Anastomosis Model Figure 2. A burst test measuring the median volume of air at time of failure. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1567692492189-IRE9BVESMGGL2MNWUCHM/Anastomosis+data+for+website+-5.jpg Pig Anastomosis Model Figure 3. Primary Failure Load mean values for tensile strength testing both raw and normalized by specimen width. https://www.bridgepts.com/rabbit-foley-catheter-urinary-infection daily 0.75 2017-04-20 https://www.bridgepts.com/minimum-inhibitory-concentration daily 0.75 2020-08-19 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1597849697545-RZCSMIMEXQJBTT3XF01U/MIC+MBC+for+website.jpg Minimum Inhibitory Concentration (MIC) / Minimum Bactericidal Concentration (MBC) Figure 1. Example photographs of minimum inhibition concentration serial dilutions. The dilution factor is indicated on the yellow bar. (A) Serial dilution of povidone iodine with the turbidity beginning at the 5th dilution. (B) Serial dilution of Test Solution 1 with the turbidity beginning at the 3rd dilution. (C) Serial dilution of Test Solution 2 with the turbidity beginning at the 4th dilution. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1597849621551-JXE2QSL44K6CXJGGNTVG/MIC+for+website+table.jpg Minimum Inhibitory Concentration (MIC) / Minimum Bactericidal Concentration (MBC) Table 1. This table compares the results of the minimum inhibition concentration (MIC) testing for povidone iodine and two test materials. This table indicates no turbidity with a “-” and turbidity with a “+”. The minimum inhibition concentration for povidone iodine was determined to be 0.63% povidone iodine. The minimum inhibition concentration for Test Solution 1 and Test Solution 2 were determined be 17.5 mM and 6.25 mM, respectively. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1597849664578-TL581O3P3XO74HIZGCXD/MBC+for+website+table+2.jpg Minimum Inhibitory Concentration (MIC) / Minimum Bactericidal Concentration (MBC) Table 2. This table compares the results of the minimum bactericidal concentration (MBC) testing for povidone iodine and two test materials. This table indicates no turbidity with a “-” and turbidity with a “+”. The minimum bactericidal concentration for povidone iodine was determined to be 0.63% povidone iodine. The minimum bactericidal concentration for Test Solution 1 and Test Solution 2 were determined be 35 mM and 25 mM, respectively. https://www.bridgepts.com/time-kill daily 0.75 2017-04-20 https://www.bridgepts.com/zone-of-clearance-inhibition daily 0.75 2020-08-19 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1597848338399-ZRU8G33FBJOT400TZTB6/ZOI+plates+for+website.jpg Zone of Clearance/Inhibition (ZOC/ZOI) Figure 2. Examples of the zone of inhibition for three different treatments. (A) Saline treated negative control, no zone of inhibition present; (B) A predicate treated positive control, large zone of inhibition present; (C) test material treated plate, small zone of inhibition present. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1597846717115-AYREDQFI1KOSIYP15RO3/ZOI+data+website.jpg Zone of Clearance/Inhibition (ZOC/ZOI) Figure 1. A comparison of the area of the corrected zone of inhibition of 5 novel antimicrobial materials compared to a predicate material positive control and a sham negative control. https://www.bridgepts.com/simple-single-species-biofilms daily 0.75 2017-04-20 https://www.bridgepts.com/complex-multi-species-biofilms daily 0.75 2020-04-16 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492719132820-7FU1O4D4L48KI852T9EY/image-asset.jpeg Complex (Multi-Species) Biofilms https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492719343264-WTLX92LM5ROHXI46XO3J/image-asset.jpeg Complex (Multi-Species) Biofilms https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492719270581-EWMW3RI9WU2TXGGETJF7/image-asset.jpeg Complex (Multi-Species) Biofilms https://www.bridgepts.com/live-dead-staining daily 0.75 2017-04-20 https://www.bridgepts.com/electron-microscopy daily 0.75 2017-04-20 https://www.bridgepts.com/tensile-testing-1 daily 0.75 2017-04-20 https://www.bridgepts.com/rabbit-peritoneal-implant-model daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492720194621-E9UH85XVIHY7VBK0IHLU/image-asset.jpeg Rabbit Peritoneal Implant Model https://www.bridgepts.com/rabbit-vaginal-mucosal-irritation-model daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492720695234-NFEH7LL912CW87FQUTQ6/image-asset.jpeg Rabbit Vaginal Mucosal Irritation Model https://www.bridgepts.com/rat-subcutaneous-implant-model daily 0.75 2020-08-19 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492721327122-Z1CPR0LJRPI7MNP0IMNY/Rat+SQ+implant+model Rat Subcutaneous Implant Model https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492721503895-VK5QZ0RYU3EPCNO3086U/image-asset.jpeg Rat Subcutaneous Implant Model https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492721443351-5X1EMB9UGT28FUCNLQ3D/image-asset.jpeg Rat Subcutaneous Implant Model https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492721559649-WCCEYGTI6VPYHTIZCCNA/image-asset.jpeg Rat Subcutaneous Implant Model https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492721607608-L5KNK9K1DC6W7QQ6O0VU/image-asset.jpeg Rat Subcutaneous Implant Model Gram stain of the infected implant shows presence of S. aureus biofilm on device surface. https://www.bridgepts.com/rabbit-foley-catheter-urinary-infection-1 daily 0.75 2017-04-20 https://www.bridgepts.com/ventilator-assisted-pneumonia-animal-model daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492722302326-JVWVMI6OQS9KQ1YCQBM1/image-asset.jpeg Ventilator-Assisted Pneumonia Animal Model The graph above shows the growth of Pseudomonas in this VAP model over 24 hours post-inoculation. Note that the Hypopharynx and Oral Cavity were not swabbed at 24 hours, so no data are shown at that time point. https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492722232723-ALGYWUZHPZB094CYEYME/Screen+Shot+2017-04-20+at+4.03.01+PM.png Ventilator-Assisted Pneumonia Animal Model https://www.bridgepts.com/tensile-testing-1-1 daily 0.75 2017-04-20 https://www.bridgepts.com/rabbit-peritoneal-implant-model-1 daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492720194621-E9UH85XVIHY7VBK0IHLU/image-asset.jpeg Rabbit Peritoneal Implant Model https://www.bridgepts.com/rat-peritoneal-fecal-contamination-model daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492723206173-QYDVZLWIZY03DQ5M5YOZ/image-asset.jpeg Rat Peritoneal (fecal) Contamination Model https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492723184819-B4IU9APAN6OVFU92HCDP/image-asset.jpeg Rat Peritoneal (fecal) Contamination Model https://www.bridgepts.com/pig-breast-implant-and-capsular-contracture-model daily 0.75 2020-04-16 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492723521696-98NYY2347CZL34B1IBNZ/image-asset.jpeg Pig Breast Implant and Capsular Contracture Model https://www.bridgepts.com/rabbit-vaginal-mucosal-irritation-model-1 daily 0.75 2017-04-20 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492720695234-NFEH7LL912CW87FQUTQ6/image-asset.jpeg Rabbit Vaginal Mucosal Irritation Model https://www.bridgepts.com/licenses-1 daily 0.75 2025-08-19 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492543470746-HS4Y9EMRA27RXL85G16Q/iStock-668528590.jpg Collaborators https://www.bridgepts.com/poster-1 daily 0.75 2018-05-03 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1492700470623-CMFW0CL64JZ3OYQCVUQG/iStock-665692688.jpg Copy of Poster 1 https://www.bridgepts.com/pig-dental-implant-model daily 0.75 2019-09-05 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1566921506287-J8QVJCMGJ6QI7BLPH93S/P8+R+POST+_+for+Website.jpg Pig Dental Implant Model Figure 1. An x-ray of titanium screws (control group) placed in the mandible of a Yucatan Mini-pig. https://www.bridgepts.com/rabbit-peri-joint-infection-model daily 0.75 2019-08-27 https://images.squarespace-cdn.com/content/v1/58f4d97917bffcda49811084/1566923536402-9HX3CGTQECRABOJADK0L/Rabbit+PJI+for+website.jpg Rabbit Peri-joint Infection Model Figure 1. Example data taken from a surgical wash study. https://www.bridgepts.com/surgical-space-rental daily 0.75 2020-08-19 https://www.bridgepts.com/bridge-pts-cited-publications daily 0.75 2024-08-26